2-Bromo-4-methylphenol → 2-Bromo-1-(cyclopropylmethoxy)-4-methylbenzene

HRID 2208130Notes

Reaction equation

[Br:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1[OH:9].Br[CH2:11][CH:12]1[CH2:14][CH2:13]1>>[Br:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1[O:9][CH2:11][CH:12]1[CH2:14][CH2:13]1

Participants

Reactant 2

HCID 231092-Bromo-4-methylphenol

HCID 81503Bromomethylcyclopropane

Product 1

HCID 435603972-Bromo-1-(cyclopropylmethoxy)-4-methylbenzene

Procedure

Starting from commercially available 2-bromo-4-methyl-phenol and bromomethyl-cyclopropane the title compound is obtained as colorless oil after distillation at 5×10−3 mbar.

Sources & evidence

ORD record: ord-1165baccf2b048bc8d76a5fa836d3841
Source dataset: uspto-grants-2016_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09376442B2

Reaction notes

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