Bromomethylcyclopropane → 2-Bromo-1-(cyclopropylmethoxy)-4-ethylbenzene

HRID 2208138Notes

Reaction equation

[Br:1][C:2]1[CH:7]=[C:6]([CH2:8][CH3:9])[CH:5]=[CH:4][C:3]=1[OH:10].Br[CH2:12][CH:13]1[CH2:15][CH2:14]1>>[Br:1][C:2]1[CH:7]=[C:6]([CH2:8][CH3:9])[CH:5]=[CH:4][C:3]=1[O:10][CH2:12][CH:13]1[CH2:15][CH2:14]1

Participants

Reactant 2

HCID 81503Bromomethylcyclopropane

HCID 166412522-Bromo-4-ethylphenol

Product 1

HCID 670333542-Bromo-1-(cyclopropylmethoxy)-4-ethylbenzene

Procedure

Starting from 2-bromo-4-ethyl-phenol (example B.a5) and commercially available bromomethyl-cyclopropane the title compound is obtained as colorless oil after distillation at 10 mbar.

Sources & evidence

ORD record: ord-1e544cf971f7484885afef9a2fd2314e
Source dataset: uspto-grants-2016_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09376442B2

Reaction notes

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