HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphate → L-tert-Leucine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphate | HCID 1061 | — |
| Reactant | Isopropylamine | HCID 6363 | — |
| Reactant | (-)-2-Aminobutyric acid | HCID 80283 | — |
| Reactant | HCID 21320258 | HCID 21320258 | — |
| Product | L-tert-Leucine | HCID 164608 | — |
Reaction Steps
L-tert-Leucine was produced with a conversion of 97% by conducting reactions using 50 mL of a mixture of 0.3 M trimethylpyruvate, 20 mM L-homoalanine, 0.45 M isopropylamine, 0.5 mM PLP, 50 mM phosphate pH 8, 35 U/mL BCTA and 30 U/mL OATA. 1.365 g of pure L-tert-leucine was obtained through purification based on solubility.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09376694B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-765ae7d06f464a2ab00b6f39812786af |
| Source note | uspto-grants-2016_06 |