HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Oxa-3-azabicyclo[3.1.1]heptane → 3-(4-Bromophenyl)-6-oxa-3-azabicyclo[3.1.1]heptane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Oxa-3-azabicyclo[3.1.1]heptane | HCID 17965857 | — |
| Reactant | HCID 117843577 | HCID 117843577 | — |
| Product | 3-(4-Bromophenyl)-6-oxa-3-azabicyclo[3.1.1]heptane | HCID 84804635 | 61% |
Reaction Steps
Prepared by the procedure, previously described for the synthesis of tert-butyl 3-(4-bromophenyl)-3,6-diazabicyclo[3.1.1]heptane-6-carboxylate, using instead 6-oxa-3-azabicyclo[3.1.1]heptane as a starting material to afford 570.0 mg (61%) of 3-(4-bromophenyl)-6-oxa-3-azabicyclo[3.1.1]heptane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09376441B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-e11d3272f5b94e3db9d646e06c792f01 |
| Source note | uspto-grants-2016_06 |