反应详情

温度

90 °C

2.8 g of p-hydroxy cinnamic acid was dissolved in 3 ml of DMSO, and 10 mg of sodium hydride of which the oil was washed by hexane was added. The mixture was stirred and heated to 90° C. under a flow of N2 gas. 5.0 g of glycidol was added gradually, heating and agitation were carried out for 1.5 hours, neutralized by adding hydrochloric acid and then the adduct of cinnamic acid and glycerin was obtained.

1. wash10 mg of sodium hydride of which the oil was washed by hexane
2. additionwas added
3. addition5.0 g of glycidol was added gradually
4. temperatureheating
5. additionby adding hydrochloric acid