HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 51704107, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 86747529 | HCID 86747529 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 51704107 | HCID 51704107 | — |
Reaction Steps
To a mechanically stirred solution of 53 (2.2 g, 9.7 mmol) in ethyl acetate (180 mL) at -15° C. was vigorously bubbled HCl gas for 30 min. The cooling bath (ethanol/ice) was removed and the solution purged with argon for 1.0 h to remove excess HCl. Concentration furnished the amine.HCl 54 as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05455243 |
| Source dataset | uspto-grants-1995_10 |
| ORD ID | ord-64751ef205ce4f4f919fe9bdb3a48749 |
| Source note | uspto-grants-1995_10 |