Glycerol → 2-Propenoic acid, 3-phenyl-

HRID 22095Notes

Reaction equation

HRID 22095 reaction equation
CO[C:3]1[CH:17]=[CH:16][CH:15]=[CH:14][C:4]=1[C:5](OC)=[C:6](OC)[C:7]([OH:9])=[O:8].C1OC1CO.S(=O)(=O)(O)O.OCC(CO)O>CS(C)=O>[C:7]([OH:9])(=[O:8])[CH:6]=[CH:5][C:4]1[CH:3]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

6

Reactant 4

HCID 753GlycerolHCID 1118Sulfuric AcidHCID 11164GlycidolHCID 54572276Trimethoxy cinnamic acid

Product 1

HCID 87842-Propenoic acid, 3-phenyl-

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Conditions

Temperature
90 °C

Procedure

4.35 g of trimethoxy cinnamic acid and 10 g of glycidol were dissolved in 5 ml of DMSO. The mixture was stirred and heated to 90° C. Catalystic amount of sulfuric acid was added, heating and agitation were carried out for 3.5 hours, and then the adduct of cinnamic acid and glycerin was obtained.

Workup

  1. temperatureheating

Sources & evidence

ORD record
ord-ff8a7db881944361986decaa997cade8
Source dataset
uspto-grants-1995_06
Patent number
US05426210

Reaction notes

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