反应详情

A solution of 7 (1.27 g) in methanol (325 ml) was hydrogenated at 15 psi in the presence of 10% Pd/C (0.65 g). The reaction mixture was filtered through celite and the filtrate was evaporated. Crystallization of the crude product from methanol gave 0.57 g of 10: mp 186°-188° C. (Lit. mp 185°-187° C.)

1. filtrationThe reaction mixture was filtered through celite
2. customthe filtrate was evaporated
3. customCrystallization of the crude product from methanol