HuagongsheHuagongshe Chemistry Print Report · For research reference only
2',3'-Didehydro-2',3'-dideoxyadenosine → Dideoxyadenosine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2',3'-Didehydro-2',3'-dideoxyadenosine | HCID 64975 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Dideoxyadenosine | HCID 20039 | 44.5% |
Reaction Steps
A solution of 7 (1.27 g) in methanol (325 ml) was hydrogenated at 15 psi in the presence of 10% Pd/C (0.65 g). The reaction mixture was filtered through celite and the filtrate was evaporated. Crystallization of the crude product from methanol gave 0.57 g of 10: mp 186°-188° C. (Lit. mp 185°-187° C.)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05455339 |
| Source dataset | uspto-grants-1995_10 |
| ORD ID | ord-51322fe2e220492a84bd0c12b2a13985 |
| Source note | uspto-grants-1995_10 |