Methylamine → HCID 178483966, compound

HRID 2209769Notes

Reaction equation

HRID 2209769 reaction equation
[C:1]([O:5][C:6]([CH:8]([C:12]1[CH:17]=[CH:16][C:15]([CH:18]2[CH2:23][CH2:22][C:21](=O)[CH2:20][CH2:19]2)=[CH:14][CH:13]=1)[CH2:9][NH:10][CH3:11])=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH3:25][NH2:26]>C(OCC)(=O)C.CO>[C:1]([O:5][C:6]([CH:8]([C:12]1[CH:17]=[CH:16][C:15]([C@H:18]2[CH2:23][CH2:22][C@H:21]([NH:26][CH3:25])[CH2:20][CH2:19]2)=[CH:14][CH:13]=1)[CH2:9][NH:10][CH3:11])=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 6329MethylamineHCID 67847036HCID 67847036, compound

Product 1

HCID 178483966HCID 178483966, compound

Reagents, catalysts & solvents 1

HCID 21584119Ethylacetate methanolSolvent

Procedure

from 4-[4-(1-tert.butoxycarbonyl-methylaminoethyl)-phenyl]-cyclohexanone and methylamine. Oil. Rf value: 0.5 (alumina, ethyl acetate/methanol=10:1, v:v).

Sources & evidence

ORD record
ord-3ce3d8fe65084c7989897ba42b8280db
Source dataset
uspto-grants-1995_10
Patent number
US05455273

Reaction notes

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