Chloroacetamide → HCID 178482803, compound

HRID 2209807Notes

Reaction equation

[Cl:1][C:2]1[CH:26]=[CH:25][C:5]([C:6]([N:8]([C@H:10]2[CH2:15][CH2:14][C@H:13](C3C=CC(CNC)=CC=3)[CH2:12][CH2:11]2)[CH3:9])=[O:7])=[CH:4][CH:3]=1.Cl[CH2:28][C:29]([NH2:31])=[O:30]>>[NH2:31][C:29]([CH2:28][C:3]1[CH:2]=[CH:26][C:25]([C@H:13]2[CH2:14][CH2:15][C@H:10]([N:8]([C:6](=[O:7])[C:5]3[CH:25]=[CH:26][C:2]([Cl:1])=[CH:3][CH:4]=3)[CH3:9])[CH2:11][CH2:12]2)=[C:5]([CH2:6][NH:8][CH3:9])[CH:4]=1)=[O:30]

Participants

Reactant 2

HCID 6580Chloroacetamide

HCID 178482784HCID 178482784, compound

Product 1

HCID 178482803HCID 178482803, compound

Procedure

from trans-N-(4-chlorobenzoyl)-N-methyl-4-(4-methylaminomethylphenyl)cyclohexylamine and chloroacetamide. Melting point: 138°-140° C.

Sources & evidence

ORD record: ord-6f0c99340dd049339fa4d2180e29de5c
Source dataset: uspto-grants-1995_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05455273

Reaction notes

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