1-Chloro-1-chloromethyl-1-silacyclopentane → HCID 19382018, compound

Participants

Reaction Steps

In the same apparatus and procedures as Example 4-ii) was prepared 15.3 g (0.079 mol) of 2,4-difluorophenylmagnesiumbromide solution in THF, and the followed by coupling with 1-chloro-1-chloromethyl-1-silacyclopentane prepared from the above procedure i) for 1hr at 60° C. In the same method as Example 1 was treated the reaction product to give 3.5 g of 1-chloromethyl -1-(2,4-difluorophenyl)-1-silacyclopentane (56°-7° C. /0.3 mmHg).

Provenance & Evidence