HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dabco → HCID 19379775, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dabco | HCID 9237 | — |
| Reactant | Octahydro-1H-pyrrolo[3,4-b]pyridine | HCID 5154241 | — |
| Reactant | 1-Cyclopropyl-7-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | HCID 9859708 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | HCID 19379775 | HCID 19379775 | — |
Reaction Steps
741 mg (3 mmol) of 1-cyclopropyl-7-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid together with 567 mg (4.5 mol) of 2,8-diazabicyclo[4.3.0]nonane and 672 mg of 1,4-diazabicyclo[2.2.2]octane are heated for two hours at 100° C. in 30 ml of N-methylpyrrolidone. The mixture is concentrated under a high vacuum, and the residue is stirred thoroughly with acetonitrile and dried at 100° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05457104 |
| Source dataset | uspto-grants-1995_10 |
| ORD ID | ord-8342d5de3d1e4151afe42e3b4fe82b20 |
| Source note | uspto-grants-1995_10 |