HCID 86749038, compound → HCID 19379917, compound

HRID 2210090Notes

Reaction equation

HRID 2210090 reaction equation
[C:1]1([CH:7]=[CH:8][CH:9]=[C:10]2[C:15](=[O:16])[CH2:14][CH2:13][CH2:12][C:11]2=[O:17])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[H][H]>[Pd].C(OCC)(=O)C>[C:1]1([CH2:7][CH2:8][CH2:9][CH:10]2[C:11](=[O:17])[CH2:12][CH2:13][CH2:14][C:15]2=[O:16])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

5

Reactant 2

HCID 86749038HCID 86749038, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 19379917HCID 19379917, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

A mixture of 6.8 g (30 mmol) of 2-(3-phenylpropenylidene)-1,3-cyclohexanedione from the preceding example, 0.7 g of 10% palladium on carbon, and 150 mL of ethyl acetate was stirred at room temperature, in an atmosphere of hydrogen, until gas uptake ceased. The catalyst was filtered with suction and the filtrate was concentrated in vacuo giving 6.7 g (97%) of the title dione as an off-white solid which was used without further purification.

Workup

  1. filtrationThe catalyst was filtered with suction
  2. concentrationthe filtrate was concentrated in vacuo
  3. customgiving 6.7 g (97%) of the title dione as an off-white solid which
  4. customwas used without further purification

Sources & evidence

ORD record
ord-e5c38d933e1343489a47f2070a69b474
Source dataset
uspto-grants-1995_10
Patent number
US05457124

Reaction notes

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