HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-Methyl-thiazol-4-yl)morpholin-5-one → 2-(2-Methyl-1,3-thiazol-4-yl)morpholine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-Methyl-thiazol-4-yl)morpholin-5-one | HCID 19974356 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | Chloroform methanol ammonia | HCID 21866414 | — |
| Product | 2-(2-Methyl-1,3-thiazol-4-yl)morpholine | HCID 19974199 | — |
Reaction Steps
Prepared analogously to Example O by reduction of 2-(2-methyl-thiazol-4-yl)morpholin-5-one with lithium aluminium hydride and purification of the base on a silica gel column with chloroform/methanol/ammonia =93:7:0.7 as eluant.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05457205 |
| Source dataset | uspto-grants-1995_10 |
| ORD ID | ord-8f926dfda0e14095b690045022b07f85 |
| Source note | uspto-grants-1995_10 |