Methane → N-[2-(4-Carboxymethoxyphenyl)-1-methylethyl]-2-(2-amino-thiazol-4-yl)morpholine dichloride

Participants

Reaction Steps

1.6 g (0.0037 mol) of N-[2-(4-carbomethoxymethoxyphenyl)1-methylethyl]-2-(2-acetamino-thiazol-4-yl)morpholine in 100 ml of 18% strength hydrochloric acid are heated to reflux under nitrogen for 48 hours. 1.5 g of active charcoal are added to the reaction solution which is thoroughly stirred and filtered. The solution is then concentrated, and the product is dried in vacuo over potassium hydroxide.

Provenance & Evidence