Methylamine → HCID 15365170, compound

HRID 2210421Notes

Reaction equation

HRID 2210421 reaction equation
Cl[C:2]1[CH:7]=[CH:6][N:5]=[CH:4][C:3]=1[S:8]([NH2:11])(=[O:10])=[O:9].[CH3:12][NH2:13]>>[CH3:12][NH:13][C:2]1[CH:7]=[CH:6][N:5]=[CH:4][C:3]=1[S:8]([NH2:11])(=[O:10])=[O:9]

Participants

3

Reactant 2

HCID 6329MethylamineHCID 1184264-Chloro-3-pyridinesulphonamide

Product 1

HCID 15365170HCID 15365170, compound

Procedure

10 g of 4-chloropyridine-3-sulfonamide are dissolved in 100 cm3 of 40% aqueous methylamine solution and the solution is introduced into a sealed tube. The tube is placed at 150° C. for 18 hours. After cooling, the reaction mixture is concentrated under vacuum (rotary evaporator) to a volume of 30 cm3. The crystalline precipitate corresponding to the title compound is collected on a filter, washed with water and dried.

Workup

  1. additionthe solution is introduced into a sealed tube
  2. temperatureAfter cooling
  3. concentrationthe reaction mixture is concentrated under vacuum (rotary evaporator) to a volume of 30 cm3
  4. customThe crystalline precipitate corresponding to the title compound is collected on a filter
  5. washwashed with water
  6. customdried

Sources & evidence

ORD record
ord-14a831cd5df24f9eb1121eea10f1b9a0
Source dataset
uspto-grants-1995_10
Patent number
US05459138

Reaction notes

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