Sodium Hydroxide → HCID 19378726, compound

HRID 2210425Notes

Reaction equation

HRID 2210425 reaction equation
C([NH:4][C:5]1[C:10]([S:11]([NH:14][C:15](=[O:17])[CH3:16])(=[O:13])=[O:12])=[CH:9][N:8]=[C:7]([Cl:18])[CH:6]=1)(=O)C.[OH-].[Na+]>O>[NH2:4][C:5]1[C:10]([S:11]([NH:14][C:15](=[O:17])[CH3:16])(=[O:13])=[O:12])=[CH:9][N:8]=[C:7]([Cl:18])[CH:6]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 19378738HCID 19378738, compound

Product 1

HCID 19378726HCID 19378726, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A solution of 0.5 g of 4-acetylamino-5-acetylaminosulfonyl-2-chloropyridine (preceding stage) in 10 cm3 of water containing 0.137 g of NaOH (2 equivalents) is brought to reflux for 15 minutes. After cooling, the solution is adjusted to a pH of 6 and the precipitate obtained is collected on a filter, washed with water and dried.

Workup

  1. temperatureto reflux for 15 minutes
  2. temperatureAfter cooling
  3. customthe precipitate obtained
  4. customis collected on a filter
  5. washwashed with water
  6. customdried

Sources & evidence

ORD record
ord-8ea0c473bd2a48eaaeacf03574253908
Source dataset
uspto-grants-1995_10
Patent number
US05459138

Reaction notes

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