Ammonium Chloride → HCID 19378709, compound

HRID 2210432Notes

Reaction equation

HRID 2210432 reaction equation
[Cl-].[NH4+].[CH3:3][C:4]1[CH:5]=[C:6]([N+:14]([O-])=O)[C:7]([S:10]([NH2:13])(=[O:12])=[O:11])=[N:8][CH:9]=1>>[NH2:14][C:6]1[C:7]([S:10]([NH2:13])(=[O:12])=[O:11])=[N:8][CH:9]=[C:4]([CH3:3])[CH:5]=1

Participants

3

Reactant 2

HCID 25517Ammonium ChlorideHCID 19378728HCID 19378728, compound

Product 1

HCID 19378709HCID 19378709, compound

Procedure

3.46 g of reduced iron and 0.53 g of ammonium chloride are added to a solution of 2.17 g of 5-methyl-3- nitropyridine-2-sulfonamide in 60 cm3 of water/alcohol (EtOH/H2O : 1/1) solution. The mixture is brought to reflux for 20 minutes and then filtered while hot. The filtrate is concentrated to a small volume and left at 4° C. for 12 hours. The crystalline precipitate obtained is collected on a filter, washed with water and dried.

Workup

  1. temperatureto reflux for 20 minutes
  2. filtrationfiltered while hot
  3. concentrationThe filtrate is concentrated to a small volume
  4. customThe crystalline precipitate obtained
  5. customis collected on a filter
  6. washwashed with water
  7. customdried

Sources & evidence

ORD record
ord-c3388ee65e5f4a3eab8975b4eeefb69c
Source dataset
uspto-grants-1995_10
Patent number
US05459138

Reaction notes

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