Acetic Anhydride → HCID 10012589, compound

Participants

Reaction Steps

3.3 cm3 of formic acid and 6.6 cm3 of acetic anhydride are kept stirring at 50° C. for 15 minutes. 1 g of 4-aminopyridine-3-sulfonamide (Preparation 2) is added to this solution and the reaction mixture is brought to reflux for 2 hours. After cooling, the crystals obtained are collected on a filter, washed with a small amount of acetic acid and then with diethyl ether and dried.

Provenance & Evidence