HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 10563902, compound → HCID 9992351, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 10563902 | HCID 10563902 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Solvent | Phosphorus oxychloride | HCID 24813 | — |
| Product | HCID 9992351 | HCID 9992351 | — |
Reaction Steps
A solution of 1 g of 4-amino-3-cyclopentylcarbonylaminosulfonylpyridine (Preparation 17) in 1 cm3 of DMF and 10 cm3 of phosphorus oxychloride is stirred at ambient temperature for 3 hours. The solvents are removed under partial vacuum (rotary evaporator) and the residue is dissolved in 10 cm3 of water. The solution is adjusted to a pH of 4 (NaHCO3) and the crystalline precipitate obtained is collected on a filter, washed with water and dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05459138 |
| Source dataset | uspto-grants-1995_10 |
| ORD ID | ord-0e3365d861e146e4afc61a5e07c584dc |
| Source note | uspto-grants-1995_10 |