Methane → HCID 53917812, compound

Participants

Reaction Steps

0.2 g of 4-amino-5-acetylaminosulfonyl-2- chloropyridine (Preparation 19) is introduced into an open round-bottomed flask placed on an oil bath at 240° C. The temperature of the oil bath is brought over a period of a half-hour from 240° C. to 270° C. The molten mass is then cooled. It is dissolved in 4 cm3 of a tepid NaHCO3 solution (2% m/v). The solution is decolored with absorbing charcoal, filtered and then adjusted to a pH of 4 using formic acid. The crystalline precipitate obtained is collected on a filter, washed with water and dried.

Provenance & Evidence