5-Bromo-2-chlorobenzoic acid → 5-Bromo-2-chloro-1-(5-n-propyl-2-thienylmethyl)benzene

HRID 221052Notes

Reaction equation

HRID 221052 reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][C:5]([Cl:11])=[C:6]([CH:10]=1)[C:7](O)=O.[CH2:12]([C:15]1[S:16][CH:17]=[CH:18][CH:19]=1)[CH2:13][CH3:14]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([Cl:11])=[C:6]([CH2:7][C:17]2[S:16][C:15]([CH2:12][CH2:13][CH3:14])=[CH:19][CH:18]=2)[CH:10]=1

Participants

3

Reactant 2

HCID 331275-Bromo-2-chlorobenzoic acidHCID 737712-Propylthiophene

Product 1

HCID 666076655-Bromo-2-chloro-1-(5-n-propyl-2-thienylmethyl)benzene

Procedure

5-Bromo-2-chlorobenzoic acid and 2-n-propylthiophene were used and treated in a manner similar to Reference Example 5 to give the target compound.

Workup

  1. additiontreated in a manner similar to Reference Example 5
  2. customto give the target compound

Sources & evidence

ORD record
ord-996ee2af99d84bdeb41df6ed71a6c875
Source dataset
uspto-grants-2012_06
Patent number
US08202984B2

Reaction notes

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