Sodium Iodide → HCID 178506581, compound

HRID 2210525Notes

Reaction equation

HRID 2210525 reaction equation
S([O-])(=O)(=O)C.[I-:6].[Na+].[CH3:8][C:9]([CH2:11][CH3:12])=O>>[I:6][CH2:8][C@H:9]1[CH2:12][CH2:11][C@H:9]([CH2:8][I:6])[CH2:12][CH2:11]1

Participants

4

Reactant 3

HCID 5238Sodium IodideHCID 6569Methyl Ethyl KetoneHCID 85257Methanesulfonate

Product 1

HCID 178506581HCID 178506581, compound

Procedure

Add 30 gms. of the mesylate prepared in step (a) to 300 ml. methylethyl ketone (MEK), then add 90 gm. sodium iodide and reflux for about 30 minutes. Remove the solvent and extract with methylene chloride to yield trans 1,4-bis iodomethyl cyclohexane.

Workup

  1. additionAdd 30 gms
  2. customRemove the solvent
  3. extractionextract with methylene chloride

Sources & evidence

ORD record
ord-7dd7bc1bb74044a6b7ce4ff610bb53f4
Source dataset
uspto-grants-1995_10
Patent number
US05459144

Reaction notes

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