Hydrochloric Acid → HCID 22419906, compound

Participants

Reaction Steps

In to a solution of 4-hydroxy-4-[4-(2-phenyl-thiazol-4-ylmethoxy)-benzyl]-semicarbazide (1.0 g, 2.7 mmol) in THF (10 mL) was added 1N HCl in ethyl ether (1.0M, 2.7 mL, 27 mmol). After stirring for 10 minutes, additional ethyl ether (10 mL) was added and the precipitated solid was filtered and dried to give a white solid, in 88% yield, m.p. 159°-160° C.

Provenance & Evidence