HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → HCID 19379070, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | HCID 54276370 | HCID 54276370 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 19379070 | HCID 19379070 | — |
Reaction Steps
In the same manner as Example, 8, 3-[4-(3-cyclopentyloxy-4-methoxyphenyl)piperidin-1-yl]-3-oxo-propionic acid methyl ester (6.7 mmol, 2.5 g), aqueous lithium hydroxide (1.0M; 8.4 mmol, 8.4 mL) in THF (70 mL) afforded the title compound as an off-white solid, mp=122°-123° C. (6.0 mmol, 2.16 g, 89%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05459151 |
| Source dataset | uspto-grants-1995_10 |
| ORD ID | ord-9c547876bf224c609d4783b7c8558753 |
| Source note | uspto-grants-1995_10 |