Sodium Hydroxide → HCID 15293911, compound

Participants

Reaction Steps

335 mg of 2-butyl-4-(1-hydroxy-2,2-dimethylpropyl)-1-[(2'-methoxalylbiphenyl-4-yl)methyl]imidazole-5-carbonitrile [prepared as described in step (a) above] were subjected to hydrolysis using 7 ml of a 1N aqueous solution of sodium hydroxide in the same manner as described in Example 10(b), to give 256 mg of the title compound as a crystalline powder, melting at 192°-194° C. (with decomposition).

Provenance & Evidence