5-Bromo-2-chlorobenzoic acid → 5-Bromo-2-chloro-1-(5-(5-chloro-2-thienyl)-2-thienylmethyl)benzene

HRID 221060Notes

Reaction equation

HRID 221060 reaction equation
[Cl:1][C:2]1[S:6][C:5]([C:7]2[S:8][CH:9]=[CH:10][CH:11]=2)=[CH:4][CH:3]=1.[Br:12][C:13]1[CH:14]=[CH:15][C:16]([Cl:22])=[C:17]([CH:21]=1)[C:18](O)=O>>[Br:12][C:13]1[CH:14]=[CH:15][C:16]([Cl:22])=[C:17]([CH2:18][C:9]2[S:8][C:7]([C:5]3[S:6][C:2]([Cl:1])=[CH:3][CH:4]=3)=[CH:11][CH:10]=2)[CH:21]=1

Participants

3

Reactant 2

HCID 331275-Bromo-2-chlorobenzoic acidHCID 125014505-Chloro-2,2'-bithiophene

Product 1

HCID 666080295-Bromo-2-chloro-1-(5-(5-chloro-2-thienyl)-2-thienylmethyl)benzene

Procedure

2-(5-Chloro-2-thienyl)thiophene and 5-bromo-2-chlorobenzoic acid were treated in a manner similar to Reference Example 5 to give the target compound.

Workup

  1. customto give the target compound

Sources & evidence

ORD record
ord-10bf0ceec4894880a51dbded6ece5b8f
Source dataset
uspto-grants-2012_06
Patent number
US08202984B2

Reaction notes

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