Methyl iodide → HCID 86749047, compound

HRID 2210694Notes

Reaction equation

HRID 2210694 reaction equation
[F:1][C:2]([F:29])([F:28])[C:3]1[CH:4]=[C:5]([CH2:13][O:14][C@H:15]2[CH2:20][CH2:19][CH2:18][N:17]([CH3:21])[C@H:16]2[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH:6]=[C:7]([C:9]([F:12])([F:11])[F:10])[CH:8]=1.[CH3:30][I:31]>C(OCC)C>[I-:31].[F:11][C:9]([F:12])([F:10])[C:7]1[CH:6]=[C:5]([CH2:13][O:14][C@H:15]2[CH2:20][CH2:19][CH2:18][N+:17]([CH3:30])([CH3:21])[C@H:16]2[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH:4]=[C:3]([C:2]([F:28])([F:1])[F:29])[CH:8]=1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 44276728HCID 44276728, compound

Product 1

HCID 86749047HCID 86749047, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound was prepared from the N-methyl amine (0.24 g, Example 10) with methyl iodide (0.178 ml) in diethyl ether (3 ml). After 62 h the white solid which formed was isolated by filtration and washed with ether, m.p.=204°-205° C. Found: C, 46.74; H, 4.29; N, 2.41. Calcd for C22H24NOF6I.0.3H2O; C, 46.79; H, 4.39; N, 2.48%.

Workup

  1. customAfter 62 h the white solid which formed
  2. customwas isolated by filtration
  3. washwashed with ether, m.p.=204°-205° C

Sources & evidence

ORD record
ord-598ebbbfcf244bf2958e5ab49bff1a64
Source dataset
uspto-grants-1995_10
Patent number
US05459270

Reaction notes

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