HCID 19047208, compound → HCID 23298800, compound

HRID 2210850Notes

Reaction equation

HRID 2210850 reaction equation
[CH3:1][Si:2]([CH3:17])([CH3:16])[C:3]#[C:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14]>C(OCC)(=O)C.[C].[Pd]>[CH3:17][Si:2]([CH3:1])([CH3:16])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14]

Participants

4

Reactant 1

HCID 19047208HCID 19047208, compound

Product 1

HCID 23298800HCID 23298800, compoundYield 89.9%

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 8857Ethyl AcetateSolvent

Procedure

At the same time, 11-trimethylsilyl-10-undecynoic acid (0.23 g) was dissolved in ethyl acetate (5 ml), and palladium-carbon (10 mg) was added to the solution. After the air within the reactor was purged with hydrogen, the mixture was stirred at room temperature for 12hours. Then, the mixture was filtered, and the filtrate was concentrated to give 11-trimethylsilylundecanoic acid (0.21 g).

Workup

  1. customAfter the air within the reactor was purged with hydrogen
  2. filtrationThen, the mixture was filtered
  3. concentrationthe filtrate was concentrated

Sources & evidence

ORD record
ord-fa1237350efb49ea88767e22f56835e8
Source dataset
uspto-grants-1995_10
Patent number
US05461036

Reaction notes

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