Hydrochloric Acid → HCID 19377835, compound

HRID 2211024Notes

Reaction equation

HRID 2211024 reaction equation
[NH2:1][C:2]([NH2:23])=[N:3][C:4](=[O:22])[C:5]1[CH:10]=[CH:9][C:8]([N:11]2[CH2:16][CH2:15][CH:14]([NH2:17])[CH2:13][CH2:12]2)=[C:7]([S:18]([CH3:21])(=[O:20])=[O:19])[CH:6]=1.[ClH:24]>O>[ClH:24].[ClH:24].[NH2:23][C:2]([NH2:1])=[N:3][C:4](=[O:22])[C:5]1[CH:10]=[CH:9][C:8]([N:11]2[CH2:16][CH2:15][CH:14]([NH2:17])[CH2:13][CH2:12]2)=[C:7]([S:18]([CH3:21])(=[O:19])=[O:20])[CH:6]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 10735834HCID 10735834, compound

Product 1

HCID 19377835HCID 19377835, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

2.5 g of N-diaminomethylene-3-methylsulphonyl-4-(4-aminopiperidino)benzamide (m.p. 239°-241°) are suspended in 75 ml of water, and 14.7 ml of 1N HCl are added, while stirring, to this suspension. After removing the solvent and lyophilizing, N-diaminomethylene-3-methylsulphonyl-4-(4-aminopiperidino)benzamide dihydrochloride is obtained, m.p. >260°.

Workup

  1. customAfter removing the solvent

Sources & evidence

ORD record
ord-7ce2cd507b174aae8667cb3e7fe315d4
Source dataset
uspto-grants-1995_10
Patent number
US05461066

Reaction notes

Loading…