反应详情

温度

140 °C

200 mg of 1-chloro-4-(4-methyl-2-thienyl)phthalazine and 100 mg of D-α-phenylethylamine were dissolved in 2 ml of N-methylpyrrolidone, and the solution was stirred at 140° C. for 8 hours. After the solution was subjected to after-treatment, it was purified by column chromatography, thereby obtaining 25 mg of (R)-1-(α-phenylethylamino)-4-(4-methyl-2-thienyl)phthalazine.

1. customwas purified by column chromatography