Hydrochloric Acid → HCID 19375602, compound

Participants

Reaction Conditions

Reaction Steps

2.8 g of 2-(2-thenoyl)-3-(4,4-dimethyl-2-oxazoline-2-yl)thiophene was added to a solution of 30 ml of concentrated hydrochloric acid, 20 ml of water and 20 ml of dioxane, and the solution was stirred at 100° C. for 8 hours. After cooling the solution, an aqueous NaCl solution was added thereto. The resultant solution was extracted with chloroform and dried. After the solvent was distilled off, the residue was purified by silica gel chromatography to obtain 0.70 g of 2-(2-thenoyl)-3-thiophene carboxylic acid.

Provenance & Evidence