HCID 19375626, compound → HCID 131719170, compound

Participants

Reaction Steps

The title compound was obtained analogous to the method described for 2-(4-(4-(7-bromo-2,3-dihydro-1,4-benzodioxin-5-yl)-1-piperazinyl)-butyl)-1,2-benzisothiazole-3(2H)-one-1,1-dioxide, dihydrochloride (Example 3) using 1-(7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)piperazine (intermediate 2a) (2.50 g, 8.54 mmol) and 2-(4-chlorobutyl)-1,2-benzisothiazole-3(2H)-one-1-oxide (Intermediate 19c) (2.20 g, 8.54 mmol). Yield: 1.90 g (41%) of the title compound, m.p. 258°-60° C.

Provenance & Evidence