反应详情

温度

65 °C

A 1-liter (L), round-bottom flask equipped with a mechanical stirrer and a reflux condenser is charged with 23.7 grams (g) of 1,3-dichloro-4,6-dinitrobenzene, 100 milliliters (mL) of methanol, 200 mL of water and 15 grams of sodium hydroxide and heated to approximately 65° C. for 8 hours. The reaction mixture is then poured into 0° C. aqueous hydrochloric acid, isolated by filtration and air-dried. The theoretical of 5-methoxy-2,4-dinitrophenol yield is 21.4 g, and the dry weight yield is 20.5 g which gives an overall 95% yield.

1. customisolated by filtration
2. customair-dried