Sodium Iodide → HCID 19375742, compound

HRID 2211383Notes

Reaction equation

HRID 2211383 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11].Cl[CH2:16][CH2:17][CH2:18][CH2:19]Br.[I-:21].[Na+]>>[I:21][CH2:16][CH2:17][CH2:18][CH2:19][O:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11]

Participants

4

Reactant 3

HCID 5238Sodium IodideHCID 813641-Bromo-4-chlorobutaneHCID 12263583Ethyl 3-(2-hydroxyphenyl)propanoate

Product 1

HCID 19375742HCID 19375742, compoundYield 85%

Procedure

The title compound was prepared in 85% yield from ethyl 3-(2-hydroxyphenyl)propionate and 4-chlorobutyl bromide according to the procedure of Preparation 36 followed by treatment with sodium iodide; the product was an oil. NMR.

Sources & evidence

ORD record
ord-0b746becc0d9469cba247e372f8e0abe
Source dataset
uspto-grants-1995_10
Patent number
US05462954

Reaction notes

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