1-Bromo-3-chloropropane → HCID 19375793, compound

HRID 2211386Notes

Reaction equation

HRID 2211386 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([OH:9])[C:6]([Br:10])=[CH:5][C:4]=1[C:11]1[CH:16]=[CH:15][C:14]([F:17])=[CH:13][CH:12]=1.Br[CH2:19][CH2:20][CH2:21][Cl:22]>>[F:17][C:14]1[CH:15]=[CH:16][C:11]([C:4]2[C:3]([O:2][CH3:1])=[CH:8][C:7]([O:9][CH2:19][CH2:20][CH2:21][Cl:22])=[C:6]([Br:10])[CH:5]=2)=[CH:12][CH:13]=1

Participants

3

Reactant 2

HCID 80061-Bromo-3-chloropropaneHCID 19375775HCID 19375775, compound

Product 1

HCID 19375793HCID 19375793, compoundYield 84%

Procedure

The title intermediate was prepared from 4-(2-methoxy-4-hydroxy-5-bromophenyl)fluorobenzene and 3-bromopropyl chloride in 84% yield by the procedure of Preparation 36. NMR

Sources & evidence

ORD record
ord-ca4b13de141c4414b5fa8f07cc29c487
Source dataset
uspto-grants-1995_10
Patent number
US05462954

Reaction notes

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