Hydrochloric Acid → HCID 15057040, compound

HRID 22115Notes

Reaction equation

HRID 22115 reaction equation
C([NH:4][CH2:5][CH2:6][C:7]1[CH:12]=[CH:11][C:10]([CH:13]([C:21]2[CH:22]=[N:23][CH:24]=[CH:25][CH:26]=2)[CH2:14][CH2:15][CH2:16][CH2:17][C:18]([OH:20])=[O:19])=[CH:9][CH:8]=1)(=O)C.Cl>>[NH2:4][CH2:5][CH2:6][C:7]1[CH:8]=[CH:9][C:10]([CH:13]([C:21]2[CH:22]=[N:23][CH:24]=[CH:25][CH:26]=2)[CH2:14][CH2:15][CH2:16][CH2:17][C:18]([OH:20])=[O:19])=[CH:11][CH:12]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 15057039HCID 15057039, compound

Product 1

HCID 15057040HCID 15057040, compound

Procedure

4.0 g of 6-(4-(2-acetylaminoethyl)phenyl)-6-(3-pyridyl)hexanoic acid are refluxed for 18 hours with 50 ml of half concentrated hydrochloric acid. The mixture is then rotary evaporated and the residue is purified by chromatography over a column of silica gel using methanol.

Workup

  1. customThe mixture is then rotary evaporated
  2. customthe residue is purified by chromatography over a column of silica gel

Sources & evidence

ORD record
ord-72a28a8e1dc24af380b089707ff453f1
Source dataset
uspto-grants-1995_06
Patent number
US05426119

Reaction notes

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