HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 5-(Aminomethyl)pyrimidine-2,4(1H,3H)-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 5-(azidomethyl)-2,4(1H,3H)-pyrimidinedione | HCID 21963027 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5-(Aminomethyl)pyrimidine-2,4(1H,3H)-dione | HCID 15218502 | 86.4% |
Reaction Steps
The solution of 5-(azidomethyl)-2,4(1H,3H)-pyrimidinedione (0.275 g, 1.64 mmol) in ethanol: water (25:5 ml) was degassed with nitrogen, palladium on carbon (5%) was added, reaction was charged with hydrogen (55 PSI) and shaken for 2 h. The reaction was filtered and concentrated to give the 5-(aminomethyl)-2,4(1H,3H)-pyrimidinedione (0.20 g, 85%) as a solid. MS found: (M+H)+=142.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07101883B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-003b32cffb874c3296ecaabeed21de8b |
| Source note | uspto-grants-2006_09 |