Hydrochloric Acid → HCID 69288600, compound

HRID 2211839Notes

Reaction equation

HRID 2211839 reaction equation
C(OC([NH:8][C@H:9]([CH2:29][C:30]1[CH:35]=[C:34]([F:36])[C:33]([F:37])=[CH:32][C:31]=1[F:38])[CH2:10][C:11]([N:13]1[CH2:19][CH2:18][CH2:17][N:16]([CH3:20])[C:15](=[O:21])[C@H:14]1[CH2:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)=[O:12])=O)(C)(C)C.[ClH:39]>O1CCOCC1>[ClH:39].[NH2:8][C@H:9]([CH2:29][C:30]1[CH:35]=[C:34]([F:36])[C:33]([F:37])=[CH:32][C:31]=1[F:38])[CH2:10][C:11]([N:13]1[CH2:19][CH2:18][CH2:17][N:16]([CH3:20])[C:15](=[O:21])[C@H:14]1[CH2:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)=[O:12]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 69290243HCID 69290243, compound

Product 1

HCID 69288600HCID 69288600, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

The title compound from Step C was dissolved in 4M hydrogen chloride in dioxane and evaporated after 2.5 h to yield the desired product.

Workup

  1. customevaporated after 2.5 h

Sources & evidence

ORD record
ord-2f1689cee2f14229a3eaafdca7c89015
Source dataset
uspto-grants-2006_09
Patent number
US07101871B2

Reaction notes

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