3-(1-Piperazinyl)-1,2-benzisothiazole monohydrochloride → HCID 21963175, compound

Participants

Reaction Steps

Starting with N-[4-(2-Chloro-acetyl)-2-isopropyl-phenyl]-acetamide (0.380 g, 1.498 mmole), and 3-piperazin-1-yl-benzo[d]isothiazole hydrochloride (0.383 g, 1.498 mmole, 1.0 eq) and following the procedure as outlined in Example 17, N-{4-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-acetyl]-2-isopropyl-phenyl}-acetamide (0.360 g, 0.825 mmole) was obtained as its hydrochloride salt from treatment with dioxane/HCl(gas).

Provenance & Evidence