HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-(chloromethyl)thiophene → 1-[4-[(5-Chlorothien-2-yl)methyl]morpholin-2-yl]methanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-(chloromethyl)thiophene | HCID 583079 | — |
| Reactant | [4-(3,4-Dichlorobenzyl)morpholin-2-yl]methylamine | HCID 10308229 | — |
| Product | 1-[4-[(5-Chlorothien-2-yl)methyl]morpholin-2-yl]methanamine | HCID 21962888 | — |
Reaction Steps
Intermediate 13 was prepared in an analogous manner to Intermediate 1 (Alternative procedure) from Intermediate 19 and 2-chloro-5-(chloromethyl)thiophene, followed by a deprotection reaction yielding the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07101882B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-189196f1f0294a6599cfc33c714682c6 |
| Source note | uspto-grants-2006_09 |