HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Fluoro-2-methylphenyl)acetic acid → N-{[4-(3,4-Dichlorobenzyl)morpholin-2-yl]methyl}-2-(4-fluoro-2-methylphenyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Fluoro-2-methylphenyl)acetic acid | HCID 5016950 | — |
| Reactant | [4-(3,4-Dichlorobenzyl)morpholin-2-yl]methylamine | HCID 10308229 | — |
| Product | N-{[4-(3,4-Dichlorobenzyl)morpholin-2-yl]methyl}-2-(4-fluoro-2-methylphenyl)acetamide | HCID 21962785 | 16.5% |
Reaction Steps
Example 19 was prepared in an analogous manner to Example 1 using a mixture of Intermediate 1 (0.055 g) and (4-fluoro-2-methylphenyl)acetic acid (0.034 g) to give the title compound (0.014 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07101882B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-603c67d76085466497d5e22693b3a7a9 |
| Source note | uspto-grants-2006_09 |