HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)acetic acid → 2-(4-Bromo-3,5-dimethyl-1H-pyrazol-1-yl)-N-{[4-(3,4-dichlorobenzyl)morpholin-2-yl]methyl}acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)acetic acid | HCID 819616 | — |
| Reactant | [4-(3,4-Dichlorobenzyl)morpholin-2-yl]methylamine | HCID 10308229 | — |
| Product | 2-(4-Bromo-3,5-dimethyl-1H-pyrazol-1-yl)-N-{[4-(3,4-dichlorobenzyl)morpholin-2-yl]methyl}acetamide | HCID 21962991 | 32.4% |
Reaction Steps
Example 35 was prepared in an analogous manner to Example 1 using a mixture of Intermediate 1 (0.056 g) and (4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)acetic acid (0.047 g) to give the title compound (0.032 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07101882B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-bda7c50451a94c7697c823097ce3ea16 |
| Source note | uspto-grants-2006_09 |