HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-((Methylsulfonyl)amino)phenyl)acetic acid → N-({(2R)-4-[(5-Chlorothien-2-yl)methyl]morpholin-2-yl}methyl)-2-{3-[(methylsulfonyl)amino]phenyl}acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-((Methylsulfonyl)amino)phenyl)acetic acid | HCID 2773885 | — |
| Reactant | HCID 68881532 | HCID 68881532 | — |
| Product | N-({(2R)-4-[(5-Chlorothien-2-yl)methyl]morpholin-2-yl}methyl)-2-{3-[(methylsulfonyl)amino]phenyl}acetamide | HCID 68880571 | 45.8% |
Reaction Steps
Example 50 was prepared in an analogous manner to Example 44 using a mixture of Intermediate 14A (0.1 g) and Intermediate 18(0.1 g) to give the title compound (0.085 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07101882B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-716c7d99ee114564b1c08488e190efa3 |
| Source note | uspto-grants-2006_09 |