1-Iodopropane → 1-(4-Benzenesulfonyl-4-methylpentyl)-3-(1-propoxy)piperidine

HRID 2212096Notes

Reaction equation

HRID 2212096 reaction equation
[C:1]1([S:7]([C:10]([CH3:22])([CH3:21])[CH2:11][CH2:12][CH2:13][N:14]2[CH2:19][CH2:18][CH2:17][CH:16]([OH:20])[CH2:15]2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:23](I)[CH2:24][CH3:25]>>[C:1]1([S:7]([C:10]([CH3:22])([CH3:21])[CH2:11][CH2:12][CH2:13][N:14]2[CH2:19][CH2:18][CH2:17][CH:16]([O:20][CH2:23][CH2:24][CH3:25])[CH2:15]2)(=[O:8])=[O:9])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 336431-IodopropaneHCID 696627361-(4-Benzenesulfonyl-4-methylpentyl)-3-hydroxypiperidine

Product 1

HCID 696635231-(4-Benzenesulfonyl-4-methylpentyl)-3-(1-propoxy)piperidine

Procedure

The title compound was prepared from 1-(4-benzenesulfonyl-4-methylpentyl)-3-hydroxypiperidine and n-propyl iodide. NMR of hydrochloride salt:

Sources & evidence

ORD record
ord-b20c5f6088d44f5cb7c35c9d176e4cf5
Source dataset
uspto-grants-2006_09
Patent number
US07101892B2

Reaction notes

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