5-(2-(4-Chlorobenzenesulphonylamino)indan-5-yl)-5-(3-pyridyl)pent-4-enoic acid → 5-(2-(Benzenesulphonylamino)indan-5-yl)-5-(3-pyridyl)pentanoic acid

HRID 22125Notes

Reaction equation

HRID 22125 reaction equation
Cl[C:2]1[CH:7]=[CH:6][C:5]([S:8]([NH:11][CH:12]2[CH2:20][C:19]3[C:14](=[CH:15][CH:16]=[C:17]([C:21]([C:28]4[CH:29]=[N:30][CH:31]=[CH:32][CH:33]=4)=[CH:22][CH2:23][CH2:24][C:25]([OH:27])=[O:26])[CH:18]=3)[CH2:13]2)(=[O:10])=[O:9])=[CH:4][CH:3]=1>[Pt]>[C:5]1([S:8]([NH:11][CH:12]2[CH2:20][C:19]3[C:14](=[CH:15][CH:16]=[C:17]([CH:21]([C:28]4[CH:29]=[N:30][CH:31]=[CH:32][CH:33]=4)[CH2:22][CH2:23][CH2:24][C:25]([OH:27])=[O:26])[CH:18]=3)[CH2:13]2)(=[O:10])=[O:9])[CH:4]=[CH:3][CH:2]=[CH:7][CH:6]=1

Participants

3

Reactant 1

HCID 541157275-(2-(4-Chlorobenzenesulphonylamino)indan-5-yl)-5-(3-pyridyl)pent-4-enoic acid

Product 1

HCID 229016365-(2-(Benzenesulphonylamino)indan-5-yl)-5-(3-pyridyl)pentanoic acid

Reagents, catalysts & solvents 1

HCID 23939PlatinumCatalyst

Procedure

Prepared from 5-(2-(4-chlorobenzenesulphonylamino)indan-5-yl)-5-(3-pyridyl)pent-4-enoic acid analogously to Example 19 by catalytic hydrogenation in the presence of platinum as catalyst.

Sources & evidence

ORD record
ord-aded652ec91147bab13483d35857416c
Source dataset
uspto-grants-1995_06
Patent number
US05426119

Reaction notes

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