反应详情

The mixture of 1-ethyl-4,4-dimethyl-7-nitro-1,2,3,4-tetrahydro-quinoline (0.28 g) and Pd/C (0.060 g, 10% wt) in 10 ml of EtOAc was placed under H2 which was provided by a balloon and stirred at RT overnight. Then the mixture was filtered through Celite®, condensed, and the residue was purified by flash column chromatography (2% of EtOAc in CH2Cl2). The titled compound was obtained as a pink oil. MS(ES+) 204.8 (M+H)+. Calc'd for C11H16N—204.31.

1. customwas provided by a balloon
2. filtrationThen the mixture was filtered through Celite®, condensed
3. customthe residue was purified by flash column chromatography (2% of EtOAc in CH2Cl2)