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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2213054Generated: October 26, 2026

Trifluoroacetic acid → HCID 21955290, compound

https://huagongshe.com/reaction/2213054

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactanttert-Butyl 5,6-dihydroimidazo(1,2-a)pyrazine-7(8H)-carboxylateHCID 21955306—
SolventDichloromethaneHCID 6344—
ProductHCID 21955290HCID 21955290—

Reaction Steps

1,1-Dimethylethyl 5,6,7,8-tetrahydroimidazo[1,2-a]pyrazin-7-carboxylate (Description 163, 505 mg, 2.26 mmol) in dichloromethane (2.5 mL) was added to stirred, cooled (0° C.) trifluoroacetic acid (5 mL) and the mixture was stirred at 0° C. for 15 minutes, then at room temperature for 45 minutes. The solvent was evaporated under reduced pressure to give the title compound. m/z (ES+) 124 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07105507B2
Source datasetuspto-grants-2006_09
ORD IDord-48b78878247741ff961ec000ecb7ef25
Source noteuspto-grants-2006_09