HCID 86591877, compound → HCID 86591876, compound

HRID 2213074Notes

Reaction equation

HRID 2213074 reaction equation
C1(C([N:6]2[C:10]3=[CH:11][N:12]=[C:13]([C:15]4[CH:16]=[N:17][C:18]([CH3:21])=[CH:19][CH:20]=4)[CH:14]=[C:9]3[C:8]([NH:22][C:23]([CH:25]3[CH2:27][CH2:26]3)=[O:24])=[N:7]2)=O)CC1>N1CCCCC1>[CH3:21][C:18]1[N:17]=[CH:16][C:15]([C:13]2[CH:14]=[C:9]3[C:8]([NH:22][C:23]([CH:25]4[CH2:27][CH2:26]4)=[O:24])=[N:7][NH:6][C:10]3=[CH:11][N:12]=2)=[CH:20][CH:19]=1

Participants

3

Reactant 1

HCID 86591877HCID 86591877, compound

Product 1

HCID 86591876HCID 86591876, compound

Reagents, catalysts & solvents 1

HCID 8082PiperidineSolvent

Procedure

Cyclopropanecarboxylic acid [1-(1-cyclopropylmethanoyl)-5-(6-methylpyridin-3-yl)-1H-pyrazolo[3,4-c]pyridin-3-yl]amide (Description 4; 196 mg, 0.542 mmol), was dissolved in piperidine (2 mL) and stirred at room temperature for 16 hours. The piperidine was removed in vacuo, and the resulting oily residue was triturated with water to give the title compound as a solid.

Workup

  1. customThe piperidine was removed in vacuo
  2. customthe resulting oily residue was triturated with water

Sources & evidence

ORD record
ord-f4b4516dc9374f67aa78d16ac3f3fb77
Source dataset
uspto-grants-2006_09
Patent number
US07105532B2

Reaction notes

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